Within the heartwarming and comedic nature of Full House, there were instances where the show tackled serious topics with great sensitivity. In season three, episode 16, titled "Tanner's Island," the viewers were taken on an emotional rollercoaster ride.

The episode begins with the Tanner family, consisting of widowed father Danny Tanner, his three daughters DJ, Stephanie, and Michelle, and his brother-in-law Jesse, taking a vacation to Hawaii. However, this sunny getaway quickly turns into a heart-wrenching experience. As they are exploring the sandy beaches and enjoying the tropical sun, Jesse's girlfriend at the time, Cindy, abruptly breaks up with him over a phone call.

The news deeply affects Jesse, who had grown quite attached to Cindy, causing him to become emotionally withdrawn. His pain is palpable as the family tries to cheer him up and support him through this difficult time. Meanwhile, Cindy's reasons for ending the relationship stem from her desire to focus on her career, leaving Jesse feeling rejected and heartbroken.

While the episode incorporates the typical humor and family dynamics that Full House is known for, the underlying sadness is ever-present.

Each family member tries to help Jesse heal, offering words of encouragement and heartfelt moments that highlight the strength of their bond. As the episode progresses, Jesse slowly begins opening up, allowing his family's love and support to mend his broken heart.

In conclusion, the saddest scene in Full House history occurs in season three, episode 16, "Tanner's Island." The episode showcases Jesse's devastating breakup and the ensuing emotional turmoil within the Tanner family. While the show is primarily known for its light-heartedness, this scene reminds viewers that even in the laughter, life's challenges can leave us feeling heartbroken.