The article discusses the five most out of control individuals featured on the reality television show "My 600lb Life." The first person mentioned is Steven Assanti, who is known for his demanding and aggressive behavior towards healthcare professionals. Despite being given the opportunity to undergo weight loss surgery, Steven's attitude caused him to be dismissed from the program. The next person highlighted is James K., who faced numerous setbacks during his weight loss journey, including hospitalizations due to his unwillingness to follow the necessary dietary guidelines.

Next on the list is Penny Saeger, who struggled with extreme obesity and medical conditions.

Despite receiving support from the show's experts, Penny failed to make changes and continued to be reliant on her family for care. The fourth person mentioned is Lisa Fleming, whose refusal to follow the recommended diet resulted in limited progress. Despite this, she was eventually able to lose weight and improve her health.

The last person discussed is Schenee Murry, who had a history of making excuses and manipulating those around her. Schenee consistently refused to follow the program and lacked the motivation to make necessary changes. Overall, the article emphasizes the difficult and often frustrating journey faced by these individuals on "My 600lb Life."