Mary's resurgence in her Christian beliefs in Young Sheldon season 7 might lead to a potential villainous transformation. The Mary Cooper in The Big Bang Theory showed traits of being vindictive and mean, unlike her softer portrayal in the prequel. Her judgmental behavior in the sequel is attributed to her strong faith in Christianity. As she adjusts back to family life after returning from Germany, she starts to lean towards her negative tendencies. Fans speculate that her husband's impending death could drive her further towards religion to cope. Despite not being a full-fledged villain in The Big Bang Theory, Mary's character is depicted as harsher compared to Young Sheldon's portrayal.

Mary's religious beliefs fuel her unpleasant interactions with her son and family in The Big Bang Theory, hinting at a potential villainous arc in Young Sheldon. Rumors of a back story of Mary turning to faith as a coping mechanism after her husband's death adds depth to her character. The spin-off featuring Georgie and Mandy is expected to focus on their lives, possibly distancing them from the Cooper family. The absence of Missy in the spin-off hints at a shift in the family dynamics, possibly leading to a new chapter in the Cooper family's story.