In the series finale of The Big Bang Theory, Sheldon and Amy win a Nobel Prize in Physics, which brings unexpected changes. As they navigate through the complications of their success, the rest of the gang deals with their own personal and professional issues while offering support to the Coopers. Leonard finally rebels against Sheldon's controlling ways, and Penny reveals she's pregnant. Despite Sheldon's behavior threatening to split the group, they reconcile at the award ceremony. Sheldon delivers a heartfelt speech, acknowledging his friends' support, and the finale provides closure for each character.