Fans of The Big Bang Theory and Friends have long speculated about a crossover between the two hit sitcoms. Some fans have expressed interest in seeing a conversation between Sheldon from TBBT and Phoebe from Friends about evolution, while others find Sheldon to be an unbearable character. In 2016, the casts of both shows were photographed together during a gala dinner. Kaley Cuoco, who played Penny on TBBT, also had an early interaction with Jennifer Aniston from Friends when she appeared in one of Aniston's movies. Despite comparisons between them, Cuoco has nothing but praise for Aniston.