Leading the series is Johnny Galecki, who shares a two-year-old son with ex-girlfriend Alaina Meyer. Their son, named Avery, was born in November 2019, one year before the two announced they were separating. The former couple appear to be on good terms and now co-parent Avery who is set to celebrate his fourth birthday this year.
The sarcastic but fiercely intelligent Sheldon Cooper is played by Jim Parsons. Jim has been in a relationship with Emmy-nominated producer Todd Spiewak for nearly 20 years - the two met on a blind date in 2002 and tied the knot in 2017.
While Kaley Cuoco, who plays Penny on the sitcom, was once romantically involved with her co-star Johnny, the two split mid-way through filming season three, and she's since found love with fellow actor, Tom Pelphrey.
Kaley and Tom met during the premiere for the final season of Tom's show Ozark in April 2022. During an interview with USA Today the next month, Kaley was already gushing that their meeting had been love at first sight.
British-born Indian actor Kunal Nayyar played Raj in The actor doesn't have children but is married to former beauty queen and actress Neha Kapur. The couple met while Kunal was back in India for a visit and officially started dating in 2008. Three years later, in 2011 the two tied the knot.
Playing Howard is Simon Helberg, who is married to actress and producer Jocelyn Towne. The couple welcomed their first child together, a daughter named Adeline, in 2012 before becoming a family of four in 2014 when their son, Wilmer, was born.
Former child actress Mayim Bialik shares two sons, Miles and Frederick, with her ex-husband Michael Stone. The couple, who wed in 2003, announced they were going their separate ways in 2012, shortly after Mayim made her debut on