Throughout its 12 seasons, The Big Bang Theory featured an impressive array of guest stars, including Elon Musk, Stephen Hawking, Carrie Fisher, and Mark Hamill. Kaley Cuoco recently shared insights into the challenges faced by guest stars on the show. Cuoco mentioned that even seasoned dramatic actors found it difficult to adjust to the pace and rhythm of a sitcom. Aarti Mann, who played Priya, corroborated Cuoco's statement, noting the adjustments she had to make under Chuck Lorre's direction. The show's success made guest stars nervous, and strict time constraints left little room for improvisation. Cuoco also admitted her hesitance about working with infants on the set, citing their unpredictable behavior.