Mayim Bialik's character, Dr. Amy Farrah Fowler, on the sitcom "The Big Bang Theory" was supposed to be a one-episode appearance but became a regular due to Jim Parsons' insistence. Parsons, who played Sheldon Cooper, fought to keep Bialik's character on the show. Bialik's character, Amy, was loved by the audience for her humor and banter. Bialik herself has a background in neurobiology, similar to Amy. Parsons and Bialik formed a close bond and became emotional on the last day of shooting. Parsons even invited Bialik to his wedding.