The article proposes that the character shift of Meemaw in The Big Bang Theory compared to her younger self in Young Sheldon could be explained by Missy's rebellious actions. It suggests that Missy running away from home in Young Sheldon could have made Meemaw realize the need for a change in her demeanor. The article emphasizes that since Missy is the only character who could influence Meemaw's personality, this storyline has the potential to fill the plot hole between the two shows.